{"id":13,"date":"2021-03-01T13:17:09","date_gmt":"2021-03-01T13:17:09","guid":{"rendered":"https:\/\/genetec.io\/?page_id=13"},"modified":"2021-12-01T22:18:11","modified_gmt":"2021-12-01T22:18:11","slug":"sharia-venture-capital","status":"publish","type":"page","link":"https:\/\/genetec.io\/?page_id=13","title":{"rendered":"Polycomb Complex"},"content":{"rendered":"\n<p>From Wikipedia:<\/p>\n\n\n\n<p><strong>Polycomb-group proteins<\/strong>\u00a0(<strong>PcG proteins<\/strong>) are a\u00a0<a href=\"https:\/\/en.wikipedia.org\/wiki\/Protein_family\">family of protein complexes<\/a>\u00a0first discovered in fruit flies that can remodel\u00a0<a href=\"https:\/\/en.wikipedia.org\/wiki\/Chromatin\">chromatin<\/a>\u00a0such that\u00a0<a href=\"https:\/\/en.wikipedia.org\/wiki\/Epigenetic\">epigenetic<\/a>\u00a0silencing of\u00a0<a href=\"https:\/\/en.wikipedia.org\/wiki\/Gene\">genes<\/a>\u00a0takes place. Polycomb-group proteins are well known for silencing\u00a0<a href=\"https:\/\/en.wikipedia.org\/wiki\/Hox_gene\">Hox genes<\/a>\u00a0through modulation of chromatin structure during\u00a0<a href=\"https:\/\/en.wikipedia.org\/wiki\/Embryonic_development\">embryonic development<\/a>\u00a0in fruit flies (<em><a href=\"https:\/\/en.wikipedia.org\/wiki\/Drosophila_melanogaster\">Drosophila melanogaster<\/a><\/em>). They derive their name from the fact that the first sign of a decrease in PcG function is often a homeotic transformation of posterior legs towards anterior legs, which have a characteristic comb-like set of bristles.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>From Wikipedia: Polycomb-group proteins\u00a0(PcG proteins) are a\u00a0family of protein complexes\u00a0first discovered in fruit flies that can remodel\u00a0chromatin\u00a0such that\u00a0epigenetic\u00a0silencing of\u00a0genes\u00a0takes place. Polycomb-group proteins are well known for silencing\u00a0Hox genes\u00a0through modulation of chromatin structure during\u00a0embryonic development\u00a0in fruit flies (Drosophila melanogaster). They derive their name from the fact that the first sign of a decrease in PcG function [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-13","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/genetec.io\/index.php?rest_route=\/wp\/v2\/pages\/13","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/genetec.io\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/genetec.io\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/genetec.io\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/genetec.io\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=13"}],"version-history":[{"count":4,"href":"https:\/\/genetec.io\/index.php?rest_route=\/wp\/v2\/pages\/13\/revisions"}],"predecessor-version":[{"id":61,"href":"https:\/\/genetec.io\/index.php?rest_route=\/wp\/v2\/pages\/13\/revisions\/61"}],"wp:attachment":[{"href":"https:\/\/genetec.io\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=13"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}